Himalaya Herbals Guggul Guggul is prescribed for the treatment of high blood cholesterol and the hardening of arteries. The herb has been used historically for centuries to support normal fat levels and metabolism in the body. Therapeutic constituents: Guggul extracts have ketonic steroid compounds known as guggulsterones. E- and Z-guggulsterones are the compounds that are responsible for lowering cholesterol and triglyceride levels in the blood. Key therapeutic benefits: Guggul lowers cholesterol levels in the blood. As a antioxidant, the herb is also responsible for boosting ‘good’ cholesterol levels. It enhances the thyroid function, which in turn regulates metabolism and aids weight loss.